Physical assessment and reference growth curves for children with 46, XY disorders of sex development.

ABSTRACT:

Importance

Impaired growth is an important factor in patients with disorders of sex development (DSD).

Objective

To profile the growth of children with 46, XY DSD.

Methods

We compared heights between 46, XY DSD children and normal boys and obtained growth curves for DSD using the λ-median coefficient of variation method. The study subjects were categorized into groups with good response and poor response to the human chorionic gonadotrophin (HCG) test according to testosterone levels and were compared height standard deviation scores (HtSDS) with normal boys.

Results

A total of 571 children with noncongenital adrenal hyperplasia (CAH) 46, XY DSD were enrolled in this study. The overall HtSDS for the DSD subjects were -0.031 ± 1.202. The HtSDS of DSD boys were l

SUBMITTER: Wu D 

PROVIDER: S-EPMC7331437 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature