Validation of semi-automated flow-mediated dilation measurement in healthy volunteers.

ABSTRACT:

Background

Flow-mediated dilation (FMD) is a non-invasive imaging modality used to measure endothelial function but has significant intra- and inter-observer variability. The use of semi-automated FMD devices could overcome this limitation. We assessed the reproducibility of same-day semi-automated FMD measurements by investigators who received basic training on the correct use of the device.

Methods

Forty-three healthy volunteers had two brachial artery FMD measurements performed 20 minutes apart using the UNEX EF 38G device, and automated outputs were produced. Images were also manually analysed using edge-detection software. The reproducibility of repeat FMD measurements within individuals was compared for automated and manual readings, and the correlation between analyti

SUBMITTER: Dobbie LJ 

PROVIDER: S-EPMC7331823 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature