Analysis of the uterine lumen in fertility-classified heifers: I. Glucose, prostaglandins, and lipids†.

ABSTRACT: Survival and growth of the bovine conceptus (embryo and associated extraembryonic membranes) are dependent on endometrial secretions or histotroph found in the uterine lumen. Previously, serial embryo transfer was used to classify heifers as high fertile (HF), subfertile (SF), or infertile (IF). Here, we investigated specific histotroph components [glucose, prostaglandins (PGs), and lipids] in the uterine lumen of day 17 pregnant and open fertility-classified heifers. Concentrations of glucose in the uterine lumen were increased by pregnancy but did not differ among fertility-classified heifers. Differences in expression of genes encoding glucose transporters and involved with glycolysis and gluconeogenesis were observed between conceptuses collected from HF and SF heifers. In the uterine

SUBMITTER: Moraes JGN 

PROVIDER: S-EPMC7331873 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature