Clinical outcome measures and scoring systems used in prospective studies of port wine stains: A systematic review.

ABSTRACT: BACKGROUND:Valid and reliable outcome measures are needed to determine and compare treatment results of port wine stain (PWS) studies. Besides, uniformity in outcome measures is crucial to enable inter-study comparisons and meta-analyses. This study aimed to assess the heterogeneity in reported PWS outcome measures by mapping the (clinical) outcome measures currently used in prospective PWS studies. METHODS:OVID MEDLINE, OVID Embase, and CENTRAL were searched for prospective PWS studies published from 2005 to May 2020. Interventional studies with a clinical efficacy assessment were included. Two reviewers independently evaluated methodological quality using a modified Downs and Black checklist. RESULTS:In total, 85 studies comprising 3,310 patients were included in which 94 clinician/obser

SUBMITTER: van Raath MI 

PROVIDER: S-EPMC7332045 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature