Treatment and surgical factors associated with longer-term glioblastoma survival: a National Cancer Database study.

ABSTRACT:

Background

Insufficient data exist to characterize factors associated with longer-term survival of glioblastoma (GBM). A population-based analysis of GBM longer-term survivors (LTS) in the United States was conducted to investigate the association between treatment, demographic, surgical factors, and longer-term survival.

Methods

From the National Cancer Database, GBM patients were identified using ICD-O-3 histology codes 9440-9442/3, 2005-2015 and were divided into routine (≤3 years) and longer-term (>3 years) overall survival (OS) groups. Univariable and multivariable logistic regression analysis was used to assess factors associated with longer-term survival. A subset analysis was performed to further investigate the association of extent of resection and treatment combin

SUBMITTER: Malay S 

PROVIDER: S-EPMC7332237 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature