Renal Outcomes in Patients Bridged to Heart Transplant With a Left Ventricular Assist Device.

ABSTRACT:

Background

Patients with end-stage heart failure are increasingly being bridged to heart transplant (BTT) with mechanical circulatory support; however the association between a left ventricular assist device (LVAD) BTT strategy and posttransplant renal outcomes is unclear. The aim of this study was to analyze the association of LVAD BTT with the development of posttransplant renal failure using a large national registry.

Methods

We queried the 2009 to 2018 United Network for Organ Sharing registry for all adults undergoing first-time heart or heart-kidney transplantation and stratified patients by use of pretransplant durable LVAD. The primary outcome of interest was posttransplant renal failure, which was evaluated with multivariable logistic regression.

Results

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SUBMITTER: Jawitz OK 

PROVIDER: S-EPMC7332375 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature