COPD Patients Have a Restricted Breathing Pattern That Persists with Increased Metabolic Demands.

ABSTRACT: A healthy respiratory system has variability from breath-to-breath and patients with COPD (PwCOPD) have abnormal variability in breath cycles. The aim of this study was to determine if interbreath-interval and tidal-volume variability, and airflow regularity change as metabolic demands increase (seated, standing, and walking) in PwCOPD as compared to controls. Sixteen PwCOPD (64.3 ± 7.9 yr, 61.3 ± 44.1% FEV₁%predicted) and 21 controls (60.2 ± 6.8 yr, 97.5 ± 16.8% FEV₁%predicted) sat, stood, and walked at their preferred-pace for five-minutes each while breathing patterns were recorded. The mean, standard deviation, and coefficient of variation of interbreath-intervals and tidal-volume, and the regularity (sample entropy) of airflow were quantified. Results were subjec

SUBMITTER: Yentes JM 

PROVIDER: S-EPMC7332397 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature