Repositioning of the global epicentre of non-optimal cholesterol.

ABSTRACT: High blood cholesterol is typically considered a feature of wealthy western countries^1,2. However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world³ and countries are using lipid-lowering medications at varying rates. These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health^4,5. However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. Here we pooled 1,127 population-based studies that measured blood lipids in 102.6 million individuals aged 18 years and older to estimate trends from 1980 to 2018 in mean total, non-HDL and HDL choles

SUBMITTER: NCD Risk Factor Collaboration (NCD-RisC) 

PROVIDER: S-EPMC7332422 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature