Ecotoxicity screening evaluation of selected pharmaceuticals and their transformation products towards various organisms.

ABSTRACT: The intensive development of medical science has led to an increase in the availability and use of pharmaceutical products. However, nowadays, most of scientific attention has been paid to the native forms of pharmaceuticals, while the transformation products (TPs) of these substances, understood herein as metabolites, degradation products, and selected enantiomers, remain largely unexplored in terms of their characterization, presence, fate and effects within the natural environment. Therefore, the main aim of this study was to evaluate the toxicity of seven native compounds belonging to different therapeutic groups (non-steroidal anti-inflammatory drugs, opioid analgesics, beta-blockers, antibacterial and anti-epileptic drugs), along with the toxicity of their 13 most important TPs. For

SUBMITTER: Grabarczyk L 

PROVIDER: S-EPMC7332481 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature