Cardiovascular, endothelial function, and immune markers in response to treatment with a polysaccharide in HIV⁺ adults in a randomized, double-blind placebo-controlled trial.

ABSTRACT:

Background and aim

Given the ongoing problems of hypertension and endothelial dysfunction in the HIV population, the primary objective of the study was to assess the cardiovascular, endothelial function, and immune markers in response to rice bran arabinoxylan compound (RBAC) treatment in a sample of HIV⁺ adults on antiretroviral therapy (ART).

Study design

A randomized, double-blind placebo-controlled trial of 6 months was used to execute the study.

Materials and methods

Forty-seven subjects were enrolled and randomly assigned to one of two study conditions (n=22 RBAC and n=25 placebo) for 6 months with assessments at baseline and 3 and 6 months. A multivariate repeated measures analysis of variance model was used to assess the differences be

SUBMITTER: Lewis JE 

PROVIDER: S-EPMC7333168 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature