Characteristics of persistent hotspots of Schistosoma mansoni in western Cote d'Ivoire.

ABSTRACT:

Background

Preventive chemotherapy with praziquantel is the cornerstone of schistosomiasis control. However, in some social-ecological settings, the prevalence and/or intensity of Schistosoma infection does not lower meaningfully despite multiple rounds of preventive chemotherapy, a phenomenon termed persistent hotspot (PHS). We assessed the characteristics of PHS in a Schistosoma mansoni-endemic area of Côte d'Ivoire.

Methods

In October 2016, a cross-sectional survey was conducted in 14 schools in the western part of Côte d'Ivoire, one year after multiple rounds of preventive chemotherapy. In each school, 50 children aged 9-12 years provided two stool samples and one urine sample. Stool samples were subjected to triplicate Kato-Katz thick smears for S. mansoni diagnosis. Ur

SUBMITTER: Assare RK 

PROVIDER: S-EPMC7333430 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature