Effectiveness of Latent TB Screening and Treatment in People Initiating Dialysis in British Columbia, Canada.

ABSTRACT:

Background

People undergoing chronic dialysis are at an increased risk of active tuberculosis (TB). In 2012, the Canadian province of British Columbia began systematically screening people initiating dialysis for latent TB using interferon-gamma release assay (IGRA), and treating when appropriate.

Objective

The objective of this study was to compare active TB rate in people who initiated dialysis and were screened using an IGRA compared with those not screened during the same period.

Design

Retrospective cohort study.

Setting

British Columbia (BC), a Canadian province of 5.0 million people with an active TB incidence of 5.1 per 100 000 population.

Participants

All people in BC who initiated at least 90 days of dialysis between January 2012 and May 2017 w

SUBMITTER: Romanowski K 

PROVIDER: S-EPMC7333484 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature