Prognostic significance of tumor size for primary invasive cutaneous melanoma: A population-based study, 2004-2016.

ABSTRACT:

Background

This study aimed to assess the independent prognostic value of tumor size compared with other clinical and pathologic features of primary invasive cutaneous melanoma (CM).

Methods

This study included 28,593 patients with primary invasive CM in Surveillance, Epidemiology, and End Results Program database diagnosed from 2004 through 2016. Tumor size was divided into five subgroups (≤6, 7-12, 13-30, 31-42, and >42 mm). The primary endpoint was melanoma-specific survival (MSS).

Results

The relationship between tumor size and survival was piecewise. After adjusting for age, sex, primary site, histopathologic cell type, Breslow thickness, ulceration, mitotic rate, regional metastasis, and distant metastasis, the hazard ratio (HR) of MSS increased with increasing

SUBMITTER: Ma Q 

PROVIDER: S-EPMC7333855 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature