Statistical Models to Assess Leg Muscle Mass in Ambulatory Children With Spastic Cerebral Palsy Using Dual-Energy X-Ray Absorptiometry.

ABSTRACT: Cerebral palsy (CP) is a movement disorder associated with small and weak muscles. Methods that accurately assess muscle mass in children with CP are scarce. The purpose of this study was to determine whether dual-energy X-ray absorptiometry (DXA) accurately estimates midleg muscle mass in ambulatory children with spastic CP. Ambulatory children with spastic CP and typically developing children 5-11 y were studied (n = 15/group). Fat-free soft tissue mass (FFST) and fat mass at the middle third of the tibia (i.e., midleg) were estimated using DXA. Muscle mass (muscle_MRI) and muscle mass corrected for intramuscular fat (muscle_MRIfc) in the midleg were estimated using magnetic resonance imaging (MRI). Statistical models were created to predict muscle_MRI and m

SUBMITTER: Zhang C 

PROVIDER: S-EPMC7333971 | biostudies-literature | 2019 Jul - Sep

REPOSITORIES: biostudies-literature