SARS-CoV-2 infection in pregnancy: A systematic review and meta-analysis of clinical features and pregnancy outcomes.

ABSTRACT:

Background

Perform a systematic review and meta-analysis of SARS-CoV-2 infection and pregnancy.

Methods

Databases (Medline, Embase, Clinicaltrials.gov, Cochrane Library) were searched electronically on 6th April and updated regularly until 8th June 2020. Reports of pregnant women with reverse transcription PCR (RT-PCR) confirmed COVID-19 were included. Meta-analytical proportion summaries and meta-regression analyses for key clinical outcomes are provided.

Findings

86 studies were included, 17 studies (2567 pregnancies) in the quantitative synthesis; other small case series and case reports were used to extract rarely-reported events and outcome. Most women (73.9%) were in the third trimester; 52.4% have delivered, half by caesarean section (48.3%). The proportion of

SUBMITTER: Khalil A 

PROVIDER: S-EPMC7334039 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature