Diversity of Enrollment in Prostate Cancer Clinical Trials: Current Status and Future Directions.

ABSTRACT:

Background

Although there are considerable racial and ethnic disparities in prostate cancer incidence and mortality in the United States and globally, clinical trials often do not reflect disease incidence across racial and ethnic subgroups. This study aims to comprehensively review the reporting of race and ethnicity data and the representation of race and ethnicity across prostate cancer treatment-, prevention-, and screening-based clinical trials.

Methods

Seventy-two global phase III and IV prevention, screening, and treatment prostate cancer clinical trials with enrollment start dates between 1987 and 2016 were analyzed in this study, representing a total of 893,378 individual trial participants. Availability and representation of race and ethnicity data by trial funding

SUBMITTER: Rencsok EM 

PROVIDER: S-EPMC7334076 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature