Lifetime sport practice and brain metabolism in Amyotrophic Lateral Sclerosis.

ABSTRACT:

Objective

To evaluate the metabolic correlates of lifetime sport practice in ALS through brain ¹⁸F-FDG-PET.

Methods

131 patients completed a questionnaire about lifetime exposures, including physical activity related to sports, hobbies and occupations, and underwent brain ¹⁸F-FDG-PET. Exposure to sports was expressed as MET (Metabolic Equivalent of Task). We considered only regular practice (at least 2 h/week, for at least three months). We compared brain metabolism between two groups: subjects who did not report regular sport practice during life (N-group) and patients who did (Y-group). The resulting significant clusters were used in each group as seed regions in an interregional correlation analysis (IRCA) to evaluate the impact of lifetime sport pra

SUBMITTER: Canosa A 

PROVIDER: S-EPMC7334468 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature