Auditory representation of learned sound sequences in motor regions of the macaque brain.

ABSTRACT: Human speech production requires the ability to couple motor actions with their auditory consequences. Nonhuman primates might not have speech because they lack this ability. To address this question, we trained macaques to perform an auditory-motor task producing sound sequences via hand presses on a newly designed device ("monkey piano"). Catch trials were interspersed to ascertain the monkeys were listening to the sounds they produced. Functional MRI was then used to map brain activity while the animals listened attentively to the sound sequences they had learned to produce and to two control sequences, which were either completely unfamiliar or familiar through passive exposure only. All sounds activated auditory midbrain and cortex, but listening to the sequences that were learned by

SUBMITTER: Archakov D 

PROVIDER: S-EPMC7334521 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature