Sacral Nerve Modulation Has No Effect on the Postprandial Response in Irritable Bowel Syndrome.

ABSTRACT:

Purpose

Irritable bowel syndrome is a common gastrointestinal disorder with a global prevalence of approximately 11%. Onset or worsening of symptoms following digestion is one of the characteristics of the condition. The present study aimed at evaluating the postprandial sensory and motor response before and after treatment with sacral nerve modulation.

Patients and methods

Twenty-one irritable bowel syndrome patients, 12 diarrhea-predominant and 9 mixed, were eligible for a 6-week sacral nerve modulation test period. Patients were investigated with multimodal impedance planimetry including a standardized meal at baseline and at the end of 2 weeks of suprasensory stimulation embedded in the 6-week sacral nerve modulation period.

Results

There was no statistical signif

SUBMITTER: Fassov J 

PROVIDER: S-EPMC7335277 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature