Short-Wave Infrared Quantum Dots with Compact Sizes as Molecular Probes for Fluorescence Microscopy.

ABSTRACT: Materials with short-wave infrared (SWIR) emission are promising contrast agents for in vivo animal imaging, providing high-contrast and high-resolution images of blood vessels in deep tissues. However, SWIR emitters have not been developed as molecular labels for microscopy applications in the life sciences, which require optimized probes that are bright, stable, and small. Here, we design and synthesize semiconductor quantum dots (QDs) with SWIR emission based on Hg_xCd_1-xSe alloy cores red shifted to the SWIR by epitaxial deposition of thin Hg_xCd_1-xS shells with a small band gap. By tuning alloy composition alone, the emission can be shifted across the visible-to-SWIR (VIR) spectra while maintaining a small and equal

SUBMITTER: Sarkar S 

PROVIDER: S-EPMC7335634 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature