Spoligotype and Drug Susceptibility Profiles of Mycobacterium tuberculosis Complex Isolates in Golestan Province, North Iran.

ABSTRACT:

Introduction

Despite the moderate incidence of tuberculosis (TB) in many parts of Iran, Golestan province had a permanently higher TB incidence rate than the national average. Moreover, Golestan province receives immigrants, mainly from TB-endemic areas of Iran and neighbor countries. Here, we aimed to characterize the circulating Mycobacterium tuberculosis complex (MTBC) isolates in terms of the spoligotype and drug resistance patterns, across Golestan province.

Materials and methods

A set of 166 MTBC isolates was collected during July 2014 to July 2015 and subjected to drug susceptibility testing for first- and second-line anti-TB drugs and spoligotyping.

Results

Of 166 MTBC isolates, 139 (83.7%) isolates were assigned to 28 spoligotype international types (S

SUBMITTER: Mansoori N 

PROVIDER: S-EPMC7335844 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature