Prevalence of Bartonella spp. Infection in Patients with Sickle Cell Disease.

ABSTRACT: Background: The inherent characteristics of the sickle cell disease (SCD), the most common genetic hematological disorder, increase the propensity of infections. Bartonella spp. are emerging and neglected bacteria. A large spectrum of clinical manifestations has been linked to bartonella bloodstream infection in the last two decades that can cause fatal outcomes, especially in immunodeficient patients. The goal of this study was to evaluate the prevalence of bartonella infection in SCD patients. Materials and Methods: We evaluated Bartonella spp. prevalence in 107 SCD patients. Blood samples and enrichment blood cultures were analyzed by molecular detection of Bartonella spp. DNA. Bartonella DNA was amplified using conventional genus-specifi

SUBMITTER: Soares TCB 

PROVIDER: S-EPMC7336878 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature