MRNA Editing, Processing and Quality Control in Caenorhabditis elegans.

ABSTRACT: While DNA serves as the blueprint of life, the distinct functions of each cell are determined by the dynamic expression of genes from the static genome. The amount and specific sequences of RNAs expressed in a given cell involves a number of regulated processes including RNA synthesis (transcription), processing, splicing, modification, polyadenylation, stability, translation, and degradation. As errors during mRNA production can create gene products that are deleterious to the organism, quality control mechanisms exist to survey and remove errors in mRNA expression and processing. Here, we will provide an overview of mRNA processing and quality control mechanisms that occur in Caenorhabditis elegans, with a focus on those that occur on protein-coding genes after transcription initi

SUBMITTER: Arribere JA 

PROVIDER: S-EPMC7337075 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature