Efficacy of a Standalone Microporous Ceramic Versus Autograft in Instrumented Posterolateral Spinal Fusion: A Multicenter, Randomized, Intrapatient Controlled, Noninferiority Trial.

ABSTRACT:

Study design

in the rest of the article written as patient- and observer-blinded, multicenter, randomized, intrapatient controlled, noninferiority trial.

Objective

The aim of this study was to determine noninferiority of a biphasic calcium-phosphate (AttraX® Putty) as a bone graft substitute for autograft in instrumented posterolateral fusion (PLF).

Summary of background data

Spinal fusion with autologous bone graft is a frequently performed surgical treatment. Several drawbacks of autografting have driven the development of numerous alternatives including synthetic ceramics. However, clinical evidence for the standalone use of these materials is limited.

Methods

This study included 100 nontraumatic adults who underwent a primary, single- or multilevel, thoraco

SUBMITTER: Lehr AM 

PROVIDER: S-EPMC7337108 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature