Separation and thickness measurements of superficial and deep slabs of the retinal nerve fiber layer in healthy and glaucomatous eyes.

ABSTRACT:

Purpose

Describe a new method to analyze retinal nerve fiber layer (RNFL) thickness maps.

Design

Cross-sectional study.

Subjects

RNFL thickness maps of healthy and glaucomatous eyes.

Methods

Optical coherence tomography (OCT) RNFL raster scans from 98 healthy and 50 glaucomatous eyes were analyzed. The RNFL thickness maps were separated into superficial (SNFL) and deep (DNFL) slabs through a partial thickness plane set at the modal thickness (mode). Association between mode and OCT signal strength (SS), age, axial length, and visual field mean deviation (VFMD) was tested (Pearson coefficient, r). Thicknesses of inferior and superior SNFL regions (i-,s-SNFL), and inferior, superior, nasal, and temporal DNFL regions (i-,s-,n-,t-DNFL) were calculated. The r

SUBMITTER: Vazquez LE 

PROVIDER: S-EPMC7337289 | biostudies-literature | 2020 Jan-Feb

REPOSITORIES: biostudies-literature