Distribution of Transmission Potential During Nonsevere COVID-19 Illness.

ABSTRACT:

Background

Patients recovering from coronavirus disease 2019 (COVID-19) often continue to test positive for the causative virus by polymerase chain reaction (PCR) even after clinical recovery, thereby complicating return-to-work plans. The purpose of this study was to evaluate transmission potential of COVID-19 by examining viral load with respect to time.

Methods

Health care personnel (HCP) at Cleveland Clinic diagnosed with COVID-19, who recovered without needing hospitalization, were identified. Threshold cycles (Ct) for positive PCR tests were obtained and viral loads calculated. The association of viral load with days since symptom onset was examined in a multivariable regression model, which was reduced by stepwise backward selection to only keep variables significant

SUBMITTER: Shrestha NK 

PROVIDER: S-EPMC7337652 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature