Transposable elements employ distinct integration strategies with respect to transcriptional landscapes in eukaryotic genomes.

ABSTRACT: Transposable elements (TEs) are ubiquitous DNA segments capable of moving from one site to another within host genomes. The extant distributions of TEs in eukaryotic genomes have been shaped by both bona fide TE integration preferences in eukaryotic genomes and by selection following integration. Here, we compare TE target site distribution in host genomes using multiple de novo transposon insertion datasets in both plants and animals and compare them in the context of genome-wide transcriptional landscapes. We showcase two distinct types of transcription-associated TE targeting strategies that suggest a process of convergent evolution among eukaryotic TE families. The integration of two precision-targeting elements are specifically associated with initiation of RNA Polymerase II transcrip

SUBMITTER: Zhang X 

PROVIDER: S-EPMC7337890 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature