Heparin-binding protein as a biomarker of gastrointestinal dysfunction in critically ill patients: a retrospective cross-sectional study in China.

ABSTRACT:

Objective

To investigate the association of plasma heparin-binding protein (HBP) with the development of acute gastrointestinal injury (AGI) in critically ill patients.

Design

Clinical retrospective cross-sectional study.

Setting

A general teaching hospital in China.

Participants

Adult patients (age ≥18 years) admitted to our department with an intensive care unit (ICU) stay ≥5 days.

Main outcome measures

HBP levels were recorded twice or more within 5 days after admission. The initial AGI grades and the worst AGI grades within 5 days after admission, the number of patients receiving total enteral nutrition (TEN) and the number of patients with feeding intolerance (FI) and with sepsis were also recorded, along with some clinical severity and outcome vari

SUBMITTER: Sun JK 

PROVIDER: S-EPMC7337894 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature