Validation of the PI-RADS language: predictive values of PI-RADS lexicon descriptors for detection of prostate cancer.

ABSTRACT:

Objectives

To assess the discriminatory power of lexicon terms used in PI-RADS version 2 to describe MRI features of prostate lesions.

Methods

Four hundred fifty-four patients were included in this retrospective, institutional review board-approved study. Patients received multiparametric (mp) MRI and subsequent prostate biopsy including MRI/transrectal ultrasound fusion biopsy and 10-core systematic biopsy. PI-RADS lexicon terms describing lesion characteristics on mpMRI were assigned to lesions by experienced readers. Positive and negative predictive values (PPV, NPV) of each lexicon term were assessed using biopsy results as a reference standard.

Results

From a total of 501 lesions, clinically significant prostate cancer (csPCa) was present in 175 lesions (34.9%).

SUBMITTER: Rudolph MM 

PROVIDER: S-EPMC7338829 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature