Outcome patterns of cervical adenocarcinoma and squamous cell carcinoma following curative surgery: before and after propensity score matching analysis of a cohort study.

ABSTRACT: To estimate the outcome patterns and predictors of curative surgery for cervical squamous cell carcinoma (SCC) and adenocarcinoma (ADC) for overall survival (OS), locoregional recurrence (LRR), and distant metastasis (DM), we enrolled 4628 patients who had received a diagnosis of cervical SCC or ADC and received curative surgery. Cox regression analysis was employed to calculate hazard ratios and confidence intervals (CIs); independent predictors were controlled for or stratified in the analysis, and the endpoint was all-cause death. Propensity score matching was conducted to create well-balanced groups. Multivariate Cox regression analysis indicated that the pathologic type of ADC, age ≥ 70 years, advanced pathologic stage, positive margin, poorly differentiated cancer, undifferentiated c

SUBMITTER: Zhang J 

PROVIDER: S-EPMC7339276 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature