Potential theranostics of circulating tumor cells and tumor-derived exosomes application in colorectal cancer.

ABSTRACT:

Background

At the present time, colorectal cancer (CRC) is still known as a disease with a high mortality rate. Theranostics are flawless scenarios that link diagnosis with therapy, including precision medicine as a critical platform that relies on the development of biomarkers particularly "liquid biopsy". Circulating tumor cells (CTCs) and tumor-derived exosomes (TDEs) in a liquid biopsy approach are of substantial importance in comparison with traditional ones, which cannot generally be performed to determine the dynamics of the tumor due to its wide restriction of range. Thus, recent attempts has shifted towards minimally noninvasive methods.

Main text

CTCs and TDEs, as significant signals emitted from the tumor microenvironment, which are also detectable in the blood, p

SUBMITTER: Vafaei S 

PROVIDER: S-EPMC7339440 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature