Katanin P60: a potential biomarker for lymph node metastasis and prognosis for non-small cell lung cancer.

ABSTRACT:

Background

This study aimed to assess the correlation of katanin P60 expression with clinical characteristics and survival profiles of surgical non-small cell lung cancer (NSCLC) patients.

Methods

Two hundred and sixty-five primary NSCLC patients treated by surgical resection were retrospectively viewed. The expression of katanin P60 in the tumor specimen was detected by the immunohistochemical (IHC) staining assay. Preoperative clinical data were collected from patients' medical records, and survival data were extracted from follow-up records.

Results

There were 127 (47.9%) and 138 (52.1%) patients with katanin P60-low expression and -high expression, respectively; in addition, patients presenting katanin P60-high+, -high++, and -high+++ expression were 62 (23.4%), 6

SUBMITTER: Wang L 

PROVIDER: S-EPMC7339556 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature