Differences in nicotine intake and effects from electronic and combustible cigarettes among dual users.

ABSTRACT:

Aim

To describe systemic nicotine exposure and subjective effects of electronic cigarettes (e-cigarettes) in people who use both e-cigarettes and cigarettes (dual users), including within-subject comparisons of e-cigarette and cigarette use.

Design

Two-arm, counterbalanced cross-over study. Participants used their usual brand of e-cigarette or cigarette during a standardized session in a 2-week study.

Setting

Hospital research ward, San Francisco, CA, USA.

Participants

Thirty-six healthy (eight women, 28 men) participants.

Measurements

Plasma nicotine was analyzed by gas chromatography-tandem mass spectrometry; nicotine withdrawal, urge to smoke and vape, affective states, craving, satisfaction and psychological reward were measured by standardized quest

SUBMITTER: St Helen G 

PROVIDER: S-EPMC7339816 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature