Investigating epidemiologic trends and the geographic distribution of patients with anal squamous cell carcinoma throughout Canada.

ABSTRACT:

Background

Anal cancer is a rare disease, constituting 0.5% of new cancer cases in the United States. The most common subtype is squamous cell carcinoma (scc). Studies in several developed nations have reported on an increasing incidence of anal cancer in recent decades, and various risk factors pertaining to the pathogenesis of the disease have been identified, including infection with the human papillomavirus, tobacco use, and immunosuppression. The epidemiology and distribution of anal scc throughout Canada remain poorly understood, however.

Methods

Using 3 population-based cancer registries, a retrospective analysis of demographic data across Canada for 1992-2010 was performed. The incidence and mortality for anal scc was examined at the levels of provinces, cities, and

SUBMITTER: Cattelan L 

PROVIDER: S-EPMC7339845 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature