Recruiting Control Participants into Stroke Biomarker Studies.

ABSTRACT: The number of scientists using -omics technologies to investigate biomarkers with the potential to gauge risk and aid in the diagnosis, treatment, and prognosis of stroke continues to rise, yet there are few resources to aid investigators in recruiting control participants. In this review, we describe two major strategies to match control participants to a stroke cohort-propensity score matching and one-to-one matching-including statistical approaches to gauge the balance between groups. We then explore the advantages and disadvantages of traditional recruitment methods including approaching spouses of enrolled stroke participants, direct recruitment from clinics, community outreach events, approaching retirement communities, and buying samples from a 3rd party vendor. Newer methods to ide

SUBMITTER: Edwardson MA 

PROVIDER: S-EPMC7340578 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature