Association of Statin Use With All-Cause and Cardiovascular Mortality in US Veterans 75 Years and Older.

ABSTRACT:

Importance

Data are limited regarding statin therapy for primary prevention of atherosclerotic cardiovascular disease (ASCVD) in adults 75 years and older.

Objective

To evaluate the role of statin use for mortality and primary prevention of ASCVD in veterans 75 years and older.

Design, setting, and participants

Retrospective cohort study that used Veterans Health Administration (VHA) data on adults 75 years and older, free of ASCVD, and with a clinical visit in 2002-2012. Follow-up continued through December 31, 2016. All data were linked to Medicare and Medicaid claims and pharmaceutical data. A new-user design was used, excluding those with any prior statin use. Cox proportional hazards models were fit to evaluate the association of statin use with outcomes. Analyse

SUBMITTER: Orkaby AR 

PROVIDER: S-EPMC7341181 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature