Association of plasma biomarkers of fruit and vegetable intake with incident type 2 diabetes: EPIC-InterAct case-cohort study in eight European countries.

ABSTRACT:

Objective

To investigate the association of plasma vitamin C and carotenoids, as indicators of fruit and vegetable intake, with the risk of type 2 diabetes.

Design

Prospective case-cohort study.

Setting

Populations from eight European countries.

Participants

9754 participants with incident type 2 diabetes, and a subcohort of 13 662 individuals from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort of 340 234 participants: EPIC-InterAct case-cohort study.

Main outcome measure

Incident type 2 diabetes.

Results

In a multivariable adjusted model, higher plasma vitamin C was associated with a lower risk of developing type 2 diabetes (hazard ratio per standard deviation 0.82, 95% confidence interval 0.76 to 0.89). A similar

SUBMITTER: Zheng JS 

PROVIDER: S-EPMC7341350 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature