Use of empiric methods to inform prostate cancer health disparities: Comparison of neighborhood-wide association study "hits" in black and white men.

ABSTRACT:

Background

Black men are more likely to die of prostate cancer (PCa) compared with white men. Factors ranging from genetics to neighborhood environment contribute to these disparities. However, unlike genetics, agnostic investigations that identify candidate variables from large-scale data, and that allow for empiric investigations into differential associations between neighborhood and PCa by race/ethnicity, to the authors' knowledge have not been well explored. Thus, herein, the authors built on their previously developed, empiric neighborhood-wide association study (NWAS) in white men and conducted a NWAS in black men to determine whether findings differed by race.

Methods

Pennsylvania Cancer Registry data were linked to US Census data. For the NWAS in non-Hispanic black

SUBMITTER: Lynch SM 

PROVIDER: S-EPMC7341673 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature