Validation of the revised Oxford classification for IgA nephropathy considering treatment with corticosteroids/immunosuppressors.

ABSTRACT: The Oxford classification for IgA nephropathy (IgAN) was updated in 2017. We have validated the revised Oxford classification considering treatment with corticosteroids/immunosuppressors. In this retrospective analysis, 871 IgAN patients were enrolled. Patients were divided into two groups, those treated with or without corticosteroids/immunosuppressors. The 20-year renal prognosis up to end-stage renal disease was assessed using the Oxford classification. In all patients, the renal survival rate was 87.5% at 10 years and 72.6% at 20 years. The T score alone was significantly related to renal prognosis in the Kaplan-Meier analysis and multivariate Cox regression analysis. In the non-treatment group (n = 445), E, S, T, and C scores were significantly related to renal survival rates, however

SUBMITTER: Moriyama T 

PROVIDER: S-EPMC7341848 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature