Total synthesis of isatindigotindoline C.

ABSTRACT: Total synthesis of isatindigotindoline C, a 3,3'-spiropyrrolidine oxindole alkaloid, is achieved in two steps using an exo-selective decarboxylative 1,3-dipolar cycloaddition as the key step. The synthesis verifies the originally assigned relative anti-stereochemistry for the bis-oxindole core of isatindigotindoline C.

SUBMITTER: Siitonen JH 

PROVIDER: S-EPMC7341895 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature