Brain Network Disruption in Whiplash.

ABSTRACT:

Background and purpose

Whiplash-associated disorders frequently develop following motor vehicle collisions and often involve a range of cognitive and affective symptoms, though the neural correlates of the disorder are largely unknown. In this study, a sample of participants with chronic whiplash injuries were scanned by using resting-state fMRI to assess brain network changes associated with long-term outcome metrics.

Materials and methods

Resting-state fMRI was collected for 23 participants and used to calculate network modularity, a quantitative measure of the functional segregation of brain region communities. This was analyzed for associations with whiplash-associated disorder outcome metrics, including scales of neck disability, traumatic distress, depression, and pain

SUBMITTER: Higgins JP 

PROVIDER: S-EPMC7342774 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature