Patient preferences for reducing bowel adverse events following prostate radiotherapy.

ABSTRACT: BACKGROUND:The Extended Prostate Cancer Index Composite (EPIC) instrument is a commonly used patient reported outcome (PRO) tool in prostate cancer clinical trials. Summary scores for EPIC subscales are calculated by averaging patient scores for attributes (e.g., side effects), implying equal weighting of the attributes in the absence of evidence showing otherwise. METHODS:We estimated patient preferences for each of the attributes included in the bowel subscale of the EPIC instrument using best-worst (B-W) scaling among a cohort of men with prostate cancer. Patients were presented with multiple tasks in which they were asked to indicate which attribute they would find most and least bothersome at different levels of severity. Analysis utilized both (simple) B-W counts and scores to estima

SUBMITTER: Mishra MV 

PROVIDER: S-EPMC7343167 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature