Occult Scaphocephaly: A Forme Fruste Phenotype of Sagittal Craniosynostosis.

ABSTRACT:

Introduction

Latent cranial suture fusions may present with mild or absent phenotypic changes that make the clinical diagnosis challenging. Recent reports describe patients with sagittal synostosis and a normal cranial index (CI), a condition termed normocephalic sagittal craniosynostosis (NSC). The goal of this study is to evaluate the shape and intracranial volume (ICV) in a cohort of NSC patients using quantitative cranial shape analysis (CSA).

Methods

We identified 19 patients (7.5 ± 2.28 years) between 2011 and 2016, who presented to our hospital with NSC. Cranial index and CSA were measured from the computed tomography image. Cranial shape analysis calculates the distances between the patient's cranial shape and its closest normal shape. Intracranial volume was measure

SUBMITTER: Mantilla-Rivas E 

PROVIDER: S-EPMC7343588 | biostudies-literature | 2020 Jul-Aug

REPOSITORIES: biostudies-literature