Cerebellar transcranial alternating current stimulation in the gamma range applied during the acquisition of a novel motor skill.

ABSTRACT: The development of novel strategies to augment motor training success is of great interest for healthy persons and neurological patients. A promising approach is the combination of training with transcranial electric stimulation. However, limited reproducibility and varying effect sizes make further protocol optimization necessary. We tested the effects of a novel cerebellar transcranial alternating current stimulation protocol (tACS) on motor skill learning. Furthermore, we studied underlying mechanisms by means of transcranial magnetic stimulation and analysis of fMRI-based resting-state connectivity. N = 15 young, healthy participants were recruited. 50 Hz tACS was applied to the left cerebellum in a double-blind, sham-controlled, cross-over design concurrently to the acquisition of a n

SUBMITTER: Wessel MJ 

PROVIDER: S-EPMC7343806 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature