Antibacterial and Antibiofilm Activity of Myrtenol against Staphylococcus aureus.

ABSTRACT: The increase in Staphylococcus aureus resistance to conventional antibacterials and persistent infections related to biofilms, as well as the low availability of new antibacterial drugs, has made the development of new therapeutic alternatives necessary. Medicinal plants are one of the main sources of bioactive molecules and myrtenol is a natural product with several biological activities, although its antimicrobial activity is little explored. Based on this, the objective of this study was to evaluate the antibacterial activity of myrtenol against S. aureus, determining the minimum inhibitory and bactericidal concentrations (MIC and MBC), investigating the possible molecular target through the analysis of molecular docking. It also aimed to evaluate the effect of its combination with anti

SUBMITTER: Cordeiro L 

PROVIDER: S-EPMC7344394 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature