Psychotic Experiences in Schizophrenia and Sensitivity to Sensory Evidence.

ABSTRACT: Perceptual inference depends on an optimal integration of current sensory evidence with prior beliefs about the environment. Alterations of this process have been related to the emergence of positive symptoms in schizophrenia. However, it has remained unclear whether delusions and hallucinations arise from an increased or decreased weighting of prior beliefs relative to sensory evidence. To investigate the relation of this prior-to-likelihood ratio to positive symptoms in schizophrenia, we devised a novel experimental paradigm which gradually manipulates perceptually ambiguous visual stimuli by disambiguating stimulus information. As a proxy for likelihood precision, we assessed the sensitivity of individual participants to sensory evidence. As a surrogate for the precision of prior belief

SUBMITTER: Weilnhammer V 

PROVIDER: S-EPMC7345814 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature