Antithrombotic Treatments in Patients with Chronic Coronary Artery Disease or Peripheral Artery Disease: A Systematic Review of Randomised Controlled Trials.

ABSTRACT:

Aims

Acetylsalicylic acid (ASA) is widely used for the prevention of atherothrombotic events in patients with chronic coronary artery disease (CAD) and peripheral artery disease (PAD), but the risk of vascular events remains high. We aimed at identifying randomised controlled trials (RCTs) on antithrombotic treatments in patients with chronic CAD or PAD.

Methods

Searches were conducted on MEDLINE, EMBASE, and CENTRAL on March 1^st, 2018. This systematic review (SR) uses a narrative synthesis to summarize the evidence for the efficacy and safety of antiplatelet and anticoagulant therapies in the population of both chronic CAD or PAD patients.

Results

Four RCTs from 27 publications were included. Study groups included 15,603 to 27,395 patients. ASA alone was t

SUBMITTER: Bauersachs R 

PROVIDER: S-EPMC7345917 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature