Species-Specific, pH-Independent, Standard Redox Potential of Selenocysteine and Selenocysteamine.

ABSTRACT: Microscopic redox equilibrium constants and standard redox potential values were determined to quantify selenolate-diselenide equilibria of biological significance. The highly composite, codependent acid-base and redox equilibria of selenolates could so far be converted into pH-dependent, apparent parameters (equilibrium constants, redox potentials) only. In this work, the selenolate-diselenide redox equilibria of selenocysteamine and selenocysteine against dithiothreitol were analyzed by quantitative nuclear magnetic resonance (NMR) methods to characterize the interfering acid-base and redox equilibria. The directly obtained, pH-dependent, conditional redox equilibrium constants were then decomposed by our method into pH-independent, microscopic constants, which characterize the two-elect

SUBMITTER: Palla T 

PROVIDER: S-EPMC7346207 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature