The cost-effectiveness of controlling dengue in Indonesia using wMel Wolbachia released at scale: a modelling study.

ABSTRACT:

Background

Release of virus-blocking Wolbachia-infected mosquitoes is an emerging disease control strategy that aims to control dengue and other arboviral infections. Early entomological data and modelling analyses have suggested promising outcomes, and wMel Wolbachia releases are now ongoing or planned in 12 countries. To help inform government, donor, or philanthropist decisions on scale-up beyond single city releases, we assessed this technology's cost-effectiveness under alternative programmatic options.

Methods

Using costing data from existing Wolbachia releases, previous dynamic model-based estimates of Wolbachia effectiveness, and a spatially explicit model of release and surveillance requirements, we predicted the costs and effectiveness of the ongoing programme in Y

SUBMITTER: Brady OJ 

PROVIDER: S-EPMC7346418 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature