Dysregulated micro-RNAs and long noncoding RNAs in cardiac development and pediatric heart failure.
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ABSTRACT:
SUBMITTER: Toni LS
PROVIDER: S-EPMC7346540 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Publications
Dysregulated micro-RNAs and long noncoding RNAs in cardiac development and pediatric heart failure.
Toni Lee S LS Hailu Frehiwet F Sucharov Carmen C CC
American journal of physiology. Heart and circulatory physiology 20200327 5
Noncoding RNAs (ncRNAs) are broadly described as RNA molecules that are not translated into protein. The investigation of dysregulated ncRNAs in human diseases such as cancer, neurological, and cardiovascular diseases has been under way for well over a decade. Micro-RNAs and long noncoding RNAs (lncRNAs) are the best characterized ncRNAs. These ncRNAs can have profound effects on the regulation of gene expression during cardiac development and disease. Importantly, ncRNAs are significant regulat ...[more]
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